3x01 - The Magnificent Seven

Sam: Dean, let me see your knife.
Dean: What for?
Sam: So I can gouge my eyes out.

Bobby: So, we're eating bacon cheeseburgers for breakfast, are we?
Dean: Well, sold my soul. Got a year to live. I ain't sweatin' the cholesterol.

Dean: All I see is the light at the end of the tunnel.
Sam: That's hellfire, Dean.

Isaac: The family that slays together....

Isaac: I've locked my keys in the car, turned my laundry pink, but I've never brought on the end of the world.

3x02 - The Kids Are Alright

Sam: Why are you following me?
Hunter: I'm interested in you.
Sam: Why?
Hunter: Because you're tall.

Sam: So let me get this straight. You want to drive all the way to Cicero just to hook up with some random chick?
Dean: She was a yoga teacher. That was the bendiest weekend of my life.

Sam: You're a demon!
Hunter: Don't be such a racist.

Lisa: Ben may not be your kid, but he wouldn't be alive if it weren't for you. That's a lot, if you ask me.
Dean: Yeah, well, you know. He's a great kid. I would have been proud to be his dad.

Dean: We'll just drag the kids, lay them out, torch them in the front lawn. That'll be great with the neighbors.

3x03 - Bad Day at Black Rock

Dean: I'm Batman!

Kubrick: Don't play with my Jesus.

Kubrick: It's God. He sent us here to do this. It's destiny.
Dean: Nope. No destiny. Just a rabbit's foot.

Kubrick: You were right about everything. Sam Winchester is more than a monster. He's the Adversary.
Gordon: And what happened to convince you?
Kubrick: God led me to him. And His will is clear.
Gordon: Okay. Glad to have you on board, Kubrick. But first things first. We got to get me the hell out of here. Because, like I told you before, Sam Winchester must die.

Dean: What the hell is wrong with you? You don’t just go around shooting people like that!
Bela: Relax, it’s a shoulder hit. I can aim. Besides, who here hasn’t shot a few people?

3x04 - Sin City

Dean: Azazel?
Casey: What, you think his friends just called him Yellow-Eyes? He had a name.

Sam: For some reason, you’re fighting on our side. Why is that, again?
Ruby: Go screw yourself, that’s why.

Dean: All you demons have such smart mouths.
Casey: It’s a gift.

Casey: So you see? Is my kind really really all that different than yours?
Dean: Well, except that, uh, demons are evil.
Casey: And humans are such a lovable bunch. Dick Cheney.
Dean: He's one of yours?
Casey: Not yet. Let's just say he's got a parking spot reserved for him downstairs.

3x05 - Bedtime Stories

Dean: I thought all those things ended with everyone living happily ever after.
Sam: No, no, not the originals. See, the Grimm Brothers stuff was kind of like the folklore of its day, full of sex, violence, cannabalism. Now, it got sanitized over the years and turned into Disney flicks and bedtime stories.
Dean: So you think the murders are what, a re-enactment? That's a little crazy.
Sam: Crazy as what? Every day of our lives?
Dean: Touche.

Dean: All right, maybe it is fairy tales. Totally messed-up fairy tales. I'll tell you one thing, there’s no way I'm kissing a damned frog.

Dean: I'm gonna stop the big bad wolf. Which is the weirdest thing I've ever said.

Sam: I think it's Snow White.
Dean: Snow White? Ah, I saw that movie. Oh, porn version anyway.

3x06 - Red Sky at Morning

Bela: You boys should learn to lock your doors. Anyone could just barge in.
Sam: Anyone just did.

Bela: Do you really think this is going to work?
Dean: Almost definitely not.

Bela: Don't you dare look down your nose at me. You're no better than I am.
Dean: We help people.
Bela: Come on! You do this out of vengeance and obsession. You're a stone's throw from being a serial killer. Whereas I on the other hand, I get paid to do a job, and I do it. So you tell me, which is healthier?

Dean: A Hand of Glory? I think I got one of those at the end of my Thai massage last week.

Bela: You know, when this is over, we should really have angry sex.
Dean: Don't objectify me.

3x07 - Fresh Blood

Dean: Bela, if we make it out of this alive, the first thing I'm gonna do is kill you.
Bela: You're not serious.
Dean: Listen to my voice, and tell me if I'm serious.

Dixon: You're a big part of why my people are nearly extinct, Gordon.
Gordon: Your "people" are going extinct because you're a bunch of mindless, bloodthirsty animals.

Dean: What do you want me to do, Sam, huh? Sit around all day writing sad poems about how I’m going to die? You know what, I’ve got one. Let’s see, what rhymes with "Shut up, Sam"?

Sam: Drop the attitude, Dean. Quit turning everything into a punchline. And you know something else? Stop trying to act like you're not afraid.
Dean: I'm not!
Sam: You're lying! And you may as well drop it cause I can see right through you.
Dean: You got no idea what you're talking about.
Sam: Yeah, I do. You're scared Dean. You're scared because your year is running out and you're still going to hell, and you're freaked.
Dean: And how do you know that?
Sam: Because I know you!
Dean: Really?
Sam: Yeah because I've been following you around my entire life! I mean I've been looking up to you since I was four, Dean. Studying you, trying to be just like my big brother. So yeah, I know you. Better that anyone else in the entire world. And this.. Is exactly how you act when you're terrified. And I mean I can't blame you. It's just...
Dean: What?
Sam: It's just I wish you would drop the show and be my brother again. Cause.. just cause.

Gordon: Sam Winchester’s the antichrist.
Bela: Ooh. I’d heard something about that…
Gordon: It’s true.
Bela: …from the Easter Bunny. Who heard it from the Tooth Fairy.

3x08 - A Very Supernatural Christmas

Young Sam: But Dad said the monsters under my bed weren't real.
Young Dean: That's 'cause he'd already checked under there. But, yeah, they're real. Almost everything's real.
Young Sam: Is Santa real?
Young Dean: No.

Sam: He punishes the wicked.
Dean: By hauling their asses up the chimney.
Sam: For starters, yeah.

Dean: What could you possibly say that's gonna sound crazy to me?
Sam: Um, Evil Santa.
Dean: Yeah, that's crazy.

Young Dean: First thing you have to know is we have the coolest dad in the world. He's a superhero.

Dean: You fudgeing touch me again, I'll fudgeing kill you.

Sam: Well, we're not dealing with the anti-Claus.
Dean: What'd Bobby say?
Sam: Uh, that we're morons.

3x09 - Malleus Maleficarum

Dean: I hate witches. They're all spewing their body liquids everywhere. It's creepy. Hell, it's downright unsanitary!

Ruby: That's what happens when you go to Hell, Dean. That's what it is. Forgetting.

Ruby: You need to help me get him ready for life without you. To fight this war on his own.
Dean: Ruby? Why do you want us to win?
Ruby: Isn't it obvious? I'm not like them. I wish I was, but I'm not. I remember what it's like.
Dean: What what's like?
Ruby: Being human.

Sam: Look, Dean, you're leaving, right? And I got to stay here in this craphole of a world... alone. So, the way I see it, if I'm gonna make it, if I'm gonna fight this war after you're gone, then I got to change.
Dean: Change into what?
Sam: Into you. I gotta be more like you.

Ruby: The answer is yes, by the way.
Dean: Sorry?
Ruby: Yes, the same thing will happen to you. It might take centuries, but sooner or later, Hell will burn away your humanity. Every hell bound soul, everyone, turns into something else. Turns you into us, so, yeah... yeah, you can count on it.

3x10 - Dream A Little Dream of Me

Dean: My father was an obsessed bastard! All that crap he dumped on me about protecting Sam, that was his crap! He's the one who couldn't protect his family! He's the one who let Mom, who wasn't there for Sam! I always was! It wasn't fair! I didn't deserve what he put on me! And I don't deserve to go to Hell!

Sam: What was Bobby doing in Pittsburgh?
Dean: I don't know, unless he was taking an extremely lame vacation.

Dean: Sam?
Sam: Yeah?
Dean: I've been doing some thinking. And well, the thing is, I don't want to die. I don't want to go to Hell.
Sam: Okay. We'll find a way to save you.
Dean: Okay, good

Dean: I take it we believe the legends.
Sam: When don't we?

Sam: The truth is, no one can save you.
Dean: What I've been telling you.
Sam: No, what I mean is no one can save you because you don't want to be saved.